recombinant rat il 6 rril 6 Search Results


recombinant rat il-6 protein (rril-6  (Cloud-Clone corp)
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Cloud-Clone corp recombinant rat il-6 protein (rril-6
<t>IL-6</t> expression in the L4-L5 segments of spinal dorsal horn following VPA treatment. (A) and (C) represent each experimental design and time of tissue collection. (B) VPA <t>down-regulated</t> <t>IL-6</t> expression in the L4-L5 segments of spinal dorsal horn induced by orofacial inflammation combined with FS stress. * P < 0.05 vs the CFA+FS+Saline group. (D) VPA did not affect the expression of IL-6 in the spinal dorsal horn of naïve rats. ns, non-significant.
Recombinant Rat Il 6 Protein (Rril 6, supplied by Cloud-Clone corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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recombinant rat il-6 protein (rril-6 - by Bioz Stars, 2026-09
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IL-6 expression in the L4-L5 segments of spinal dorsal horn following VPA treatment. (A) and (C) represent each experimental design and time of tissue collection. (B) VPA down-regulated IL-6 expression in the L4-L5 segments of spinal dorsal horn induced by orofacial inflammation combined with FS stress. * P < 0.05 vs the CFA+FS+Saline group. (D) VPA did not affect the expression of IL-6 in the spinal dorsal horn of naïve rats. ns, non-significant.

Journal: Brain research bulletin

Article Title: Valproate attenuates somatic hyperalgesia induced by orofacial inflammation combined with stress through inhibiting spinal IL-6 and STAT1 phosphorylation

doi: 10.1016/j.brainresbull.2024.110889

Figure Lengend Snippet: IL-6 expression in the L4-L5 segments of spinal dorsal horn following VPA treatment. (A) and (C) represent each experimental design and time of tissue collection. (B) VPA down-regulated IL-6 expression in the L4-L5 segments of spinal dorsal horn induced by orofacial inflammation combined with FS stress. * P < 0.05 vs the CFA+FS+Saline group. (D) VPA did not affect the expression of IL-6 in the spinal dorsal horn of naïve rats. ns, non-significant.

Article Snippet: Recombinant rat IL-6 protein (rrIL-6, Cloud-Clone Corp., Wuhan, China) was dissolved into the dose of 20 ng/10 μL with saline (0.9%), which was administered intrathecally.

Techniques: Expressing, Saline

Intrathecal injection of rrIL-6 reversed anti-nociceptive effect of VPA on somatic hyperalgesia induced by orofacial inflammation combined with FS stress. (A) Experimental design for single injection of rrIL-6 and behavior tests of the thermal withdrawal latency and mechanical withdrawal threshold. (B) Experimental design for consecutive injection of rrIL-6 and timeline of the thermal withdrawal latency and mechanical withdrawal threshold. Rats were treated with VPA or saline intraperitoneally for 5 days, rrIL-6/saline were administered intrathecally 1 h after last VPA injection for single injection of rrIL-6 or 5 day consecutive injection of rrIL-6 after last FS. The behavioral tests for thermal withdrawal latency and mechanical withdrawal threshold were assessed before and after rrIL-6 injection. d, day; T, thermal withdrawal latency; M, mechanical withdrawal threshold; CFA, complete Freund’s adjuvant; FS, forced swim; VPA, valproate; rrIL-6, recombinant rat IL-6. (C, D) The mechanical withdrawal threshold (C) and thermal withdrawal latency (D) were significantly decreased after single injection of rrIL-6. (E, F) The mechanical withdrawal threshold (E) and thermal withdrawal latency (F) were significantly decreased after consecutive injection of rrIL-6. *, ***, **** P < 0.05, 0.001, 0.0001 vs pre-IL-6, respectively. # , ## , ### , #### P < 0.05, 0.01, 0.001, 0.0001 vs the CFA+FS+VPA+Saline group at the same time point, respectively.

Journal: Brain research bulletin

Article Title: Valproate attenuates somatic hyperalgesia induced by orofacial inflammation combined with stress through inhibiting spinal IL-6 and STAT1 phosphorylation

doi: 10.1016/j.brainresbull.2024.110889

Figure Lengend Snippet: Intrathecal injection of rrIL-6 reversed anti-nociceptive effect of VPA on somatic hyperalgesia induced by orofacial inflammation combined with FS stress. (A) Experimental design for single injection of rrIL-6 and behavior tests of the thermal withdrawal latency and mechanical withdrawal threshold. (B) Experimental design for consecutive injection of rrIL-6 and timeline of the thermal withdrawal latency and mechanical withdrawal threshold. Rats were treated with VPA or saline intraperitoneally for 5 days, rrIL-6/saline were administered intrathecally 1 h after last VPA injection for single injection of rrIL-6 or 5 day consecutive injection of rrIL-6 after last FS. The behavioral tests for thermal withdrawal latency and mechanical withdrawal threshold were assessed before and after rrIL-6 injection. d, day; T, thermal withdrawal latency; M, mechanical withdrawal threshold; CFA, complete Freund’s adjuvant; FS, forced swim; VPA, valproate; rrIL-6, recombinant rat IL-6. (C, D) The mechanical withdrawal threshold (C) and thermal withdrawal latency (D) were significantly decreased after single injection of rrIL-6. (E, F) The mechanical withdrawal threshold (E) and thermal withdrawal latency (F) were significantly decreased after consecutive injection of rrIL-6. *, ***, **** P < 0.05, 0.001, 0.0001 vs pre-IL-6, respectively. # , ## , ### , #### P < 0.05, 0.01, 0.001, 0.0001 vs the CFA+FS+VPA+Saline group at the same time point, respectively.

Article Snippet: Recombinant rat IL-6 protein (rrIL-6, Cloud-Clone Corp., Wuhan, China) was dissolved into the dose of 20 ng/10 μL with saline (0.9%), which was administered intrathecally.

Techniques: Injection, Saline, Adjuvant, Recombinant